Gene-expression profiling in human cutaneous melanoma
نویسندگان
چکیده
منابع مشابه
Gene expression profiling of primary cutaneous melanoma and clinical outcome.
BACKGROUND Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective collections of frozen tumors. To identify differentially expressed genes that may be involved in melanoma progression and prognosis, we investigated the relationship between gene expression profiles and clinical outcome in a cohort of patients with primary melanoma. ...
متن کاملGene Expression Profiling for Melanoma
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Background Classification of cancer subtypes by means of microarray signatures is becoming increasingly difficult to ignore as a potential to transform pathological diagnosis nonetheless, measurement of Indicator genes in routine practice appears to be arduous. In a preceding published study, we utilized real-time PCR measurement of Indicator genes in acute lymphoid leukaemia (ALL) and acute m...
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متن کاملRegulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma.
PURPOSE RUNX3 is a known tumor suppressor gene in several carcinomas. Aberration in RUNX3 expression has not been described for cutaneous melanoma. Therefore, we assessed the expression of RUNX3 in cutaneous melanoma and its regulatory mechanisms relative to tumor progression. EXPERIMENTAL DESIGN The expression of RUNX3 mRNA and miR-532-5p (microRNA) was assessed in melanoma lines and in prim...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2003
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1206448